SCHEMBL18458494

SCHEMBL18458494

CCCNc1ccc(-c2ccc(-c3ccc(CC)cc3)cc2F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 3/20 0.39
▸ FAAH O00519 1/20 0.39
▸ UCHL1 P09936 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ APAF1 O14727 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ ALOX12 P18054 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ RORC P51449 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20209758 0.96 RARB (0.41) RARBFAAHUCHL1MEN1APAF1
SCHEMBL18458502 0.92 RARB (0.42) RARBFAAHUCHL1MEN1APAF1
SCHEMBL20209759 0.86 MAPT (0.43) RARBMEN1ALDH1A1POLBGAA
SCHEMBL19007867 0.86 RARB (0.43) RARBFAAHRARARARGKIF11
SCHEMBL13253648 0.86 RARB (0.43) RARBFAAHRARARARGKIF11
SCHEMBL18901806 0.85 FAAH (0.40) RARBFAAHUCHL1MEN1POLB
SCHEMBL18866790 0.84 MAPT (0.41) FAAHUCHL1MEN1APAF1USP2
SCHEMBL19864918 0.82 TNIK (0.35) RARBMEN1MAPTKMT2ARORC
SCHEMBL9999852 0.81 RARB (0.48) RARBMAPTHSD17B10L3MBTL1RARA
SCHEMBL30232659 0.81 RARB (0.48) RARBMAPTHSD17B10L3MBTL1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 — — US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 — — US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 — — US disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 — — US disclosed
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 — — US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 — — US disclosed
US-20210223635-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-07-22 — — US disclosed
US-20210171831-A1 ALIGNMENT AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-06-10 — — US disclosed
US-20210071084-A1 SPONTANEOUS ALIGNMENT ASSISTANT FOR LIQUID CRYSTAL COMPOSITIONS DIC CORPORATION (JP) 2021-03-11 — — US disclosed
US-10927300-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2021-02-23 — — US disclosed
US-20170218271-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-03 — — US disclosed
US-20170210986-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-07-27 — — US disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 — — US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 — — US disclosed
EP-3173457-A1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME DIC Corporation (JP) 2017-05-31 — — EP disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 — — US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 — — US disclosed
US-9624434-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-04-18 — — US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 — — US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN RARB 3761/4885FAAH 3694/4885UCHL1 3052/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885FAAH 3765/4885UCHL1 3949/4885
US-20210071084-A1 SPONTANEOUS ALIGNMENT ASSISTANT FOR LIQUID CRYSTAL COMPOSITIONS VAC14, VAPA, SFN RARB 3761/4885FAAH 3694/4885UCHL1 3052/4885
US-10927300-B2 Spontaneous alignment assistant for liquid crystal compositions KTN1, KCNA1, KNTC1 RARB 3790/4885FAAH 3324/4885UCHL1 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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