SCHEMBL202105

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL201796	0.94	GSTP1 (0.52)	GSTP1FFAR1MAPTTSHRL3MBTL1
	SCHEMBL2317714	0.93	MAPT (0.59)	GSTP1FFAR1MAPTTSHRL3MBTL1
	SCHEMBL2705735	0.93	MAPT (0.48)	GSTP1FFAR1MAPTTSHRL3MBTL1
	Hydrochloric Acid SCHEMBL203838	0.92	MAPT (0.47)	GSTP1FFAR1MAPTTSHRL3MBTL1
	SCHEMBL201364	0.92	TSHR (0.55)	GSTP1FFAR1MAPTTSHRL3MBTL1
	SCHEMBL203129	0.91	MAPT (0.53)	GSTP1FFAR1MAPTTSHRL3MBTL1
	SCHEMBL2321750	0.90	FFAR1 (0.53)	GSTP1FFAR1MAPTTSHRL3MBTL1
	SCHEMBL201233	0.90	MAPT (0.57)	GSTP1MAPTTSHRL3MBTL1LMNA
	SCHEMBL202775	0.90	GSTP1 (0.56)	GSTP1FFAR1MAPT
	SCHEMBL19471097	0.90	MAPT (0.46)	GSTP1FFAR1MAPTTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.