Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593496 | 0.72 | — | — | |
| SCHEMBL15056263 | 0.70 | — | — | |
| SCHEMBL5560856 | 0.68 | GRM2 (0.33) | — | |
| SCHEMBL4039600 | 0.68 | GRM4 (0.37) | ALDH1A1 | |
| SCHEMBL6799921 | 0.68 | GRM2 (0.33) | — | |
| SCHEMBL4039603 | 0.68 | GRM4 (0.37) | ALDH1A1 | |
| SCHEMBL6607890 | 0.68 | PDE4A (0.34) | — | |
| SCHEMBL6060835 | 0.66 | CYP3A4 (0.33) | — | |
| SCHEMBL24867781 | 0.65 | — | — | |
| SCHEMBL17165739 | 0.65 | GRM2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |