Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060486 | 0.87 | EP300 (0.33) | CYP3A4EP300HIF1ACREBBPPTGES | |
| SCHEMBL4811979 | 0.85 | NPSR1 (0.33) | CYP3A4 | |
| SCHEMBL5072440 | 0.84 | AKT1 (0.36) | — | |
| SCHEMBL6060516 | 0.83 | AKT1 (0.40) | — | |
| SCHEMBL4803249 | 0.83 | AKT1 (0.39) | CYP3A4ACHE | |
| SCHEMBL6061003 | 0.82 | AKT1 (0.42) | — | |
| SCHEMBL6060420 | 0.82 | AKT1 (0.42) | — | |
| SCHEMBL4817340 | 0.79 | RAB9A (0.33) | — | |
| SCHEMBL6060991 | 0.78 | HSD11B1 (0.37) | — | |
| SCHEMBL4808452 | 0.76 | AKT1 (0.35) | CYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006045246-A1 | CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2006-05-04 | — | — | WO | disclosed |