Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 6/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021209 | 1.00 | PARP10 (0.36) | PARP10PARP15SCN9ABACE1BACE2 | |
| SCHEMBL2013399 | 0.84 | HIF1A (0.36) | PARP10PARP15NPC1RAB9A | |
| SCHEMBL2015019 | 0.84 | HIF1A (0.36) | PARP10PARP15NPC1RAB9A | |
| SCHEMBL2013400 | 0.84 | HIF1A (0.36) | PARP10PARP15NPC1RAB9A | |
| SCHEMBL10127747 | 0.81 | MEN1 (0.43) | NPC1RAB9A | |
| SCHEMBL16207957 | 0.81 | PARP10 (0.42) | PARP10PARP15SCN9APDK2 | |
| SCHEMBL16207956 | 0.81 | PARP10 (0.42) | PARP10PARP15SCN9APDK2 | |
| SCHEMBL16318807 | 0.72 | HSD11B1 (0.40) | BACE1NPC1RAB9A | |
| SCHEMBL17503852 | 0.72 | CHRNB4 (0.43) | — | |
| SCHEMBL12520629 | 0.72 | NQO1 (0.38) | PDK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512474-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073845-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | disclosed |