Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214602 | 0.89 | HDAC3 (0.57) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL20214552 | 0.85 | RAB9A (0.62) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL9985455 | 0.82 | RAB9A (0.61) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL34464780 | 0.82 | RAB9A (0.61) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL20214793 | 0.81 | CA1 (0.49) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL20226796 | 0.81 | HDAC3 (0.61) | RAB9ANPC1HDAC1HDAC8HDAC6 | |
| SCHEMBL22071360 | 0.80 | CA1 (0.54) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL20214331 | 0.77 | RAB9A (0.51) | RAB9ANPC1SMPD1NR1H4HDAC1 | |
| SCHEMBL20214613 | 0.77 | HDAC6 (0.60) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL20214711 | 0.73 | NPC1 (0.45) | CA1CA2CA9RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181175-A1 | BORONIC DERIVATIVES OF HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA | 2020-06-11 | — | — | US | claimed |
| WO-2018102261-A2 | BORONIC DERIVATIVES HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2018-06-07 | — | — | WO | claimed |
| US-11046715-B2 | Boronic derivatives of hydroxamates as anticancer agents | XAVIER UNIVERSITY OF LOUISIANA (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200181175-A1 | BORONIC DERIVATIVES OF HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA | 2020-06-11 | — | — | US | disclosed |
| WO-2018102261-A2 | BORONIC DERIVATIVES HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181175-A1 | BORONIC DERIVATIVES OF HYDROXAMATES AS ANTICANCER AGENTS | BCOR, BRDT, HDAC1 | CA1 2223/4885CA2 1088/4885CA9 941/4885 |
| US-11046715-B2 | Boronic derivatives of hydroxamates as anticancer agents | BCOR, BRDT, HDAC1 | CA1 2223/4885CA2 1088/4885CA9 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.