Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954331 | 0.91 | NR4A2 (0.48) | KDRCYP4F2CYP4A11NR4A2MRGPRX4 | |
| SCHEMBL17954221 | 0.86 | CYP4F2 (0.51) | KDRCYP4F2CYP4A11NR4A2MRGPRX4 | |
| SCHEMBL12635690 | 0.84 | MAOB (0.60) | CYP4F2CYP4A11NR4A2MRGPRX4MAOB | |
| SCHEMBL3683352 | 0.81 | MRGPRX4 (0.61) | CYP4F2CYP4A11NR4A2MRGPRX4MAOB | |
| SCHEMBL9454030 | 0.81 | GRM5 (0.54) | KDRCYP4F2CYP4A11MAOBTSHR | |
| SCHEMBL379281 | 0.81 | MAOB (0.67) | CYP4F2CYP4A11NR4A2MRGPRX4MAOB | |
| SCHEMBL20215165 | 0.80 | FFAR1 (0.54) | NR4A2MRGPRX4MAOBSYKERN1 | |
| SCHEMBL2137838 | 0.79 | MRGPRX4 (0.69) | CYP4F2CYP4A11NR4A2MRGPRX4MAOB | |
| SCHEMBL20215168 | 0.79 | IDH1 (0.46) | KDRTSHRDHODH | |
| SCHEMBL20799468 | 0.79 | TSHR (0.50) | CYP4F2CYP4A11NR4A2MRGPRX4ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988627-B2 | Formats for organic compounds for use in RNA interference | NOVARTIS AG (CH) | 2018-06-05 | — | — | US | disclosed |