Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20215364 | 0.91 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL20215351 | 0.86 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL20215344 | 0.83 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL20215320 | 0.83 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL20215365 | 0.82 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL20215342 | 0.81 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL20215347 | 0.81 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL19906520 | 0.79 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL20215346 | 0.78 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL19906588 | 0.78 | P2RX7 (0.64) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988373-B2 | Nitrogen-containing six-membered cyclic derivatives and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2018-06-05 | — | — | US | disclosed |
| US-9988373-B2 | Nitrogen-containing six-membered cyclic derivatives and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2018-06-05 | — | — | US | disclosed |