Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202478 | 0.86 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL202690 | 0.82 | PDE10A (0.36) | MAP4K4 | |
| SCHEMBL204124 | 0.74 | GPR119 (0.33) | — | |
| SCHEMBL12888419 | 0.72 | GBA1 (0.47) | TLR7TLR8NUDT1MAP4K4 | |
| SCHEMBL1232845 | 0.71 | GBA1 (0.46) | TLR7TLR8NUDT1MAP4K4 | |
| SCHEMBL1232270 | 0.70 | GBA1 (0.38) | TLR7TLR8NUDT1MAP4K4 | |
| SCHEMBL1233343 | 0.69 | GBA1 (0.42) | TLR7TLR8NUDT1MAP4K4 | |
| SCHEMBL202425 | 0.69 | MAP4K4 (0.38) | MAP4K4 | |
| SCHEMBL12020795 | 0.68 | TLR7 (0.44) | TLR7TLR8 | |
| SCHEMBL1773379 | 0.68 | TLR7 (0.40) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |