Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | TTK | P33981 | 7/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 6/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 5/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217912 | 0.83 | CYP3A4 (0.43) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217751 | 0.81 | CYP3A4 (0.55) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217592 | 0.80 | CYP3A4 (0.53) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217617 | 0.80 | CYP3A4 (0.49) | CYP3A4TTKAURKBINCENP | |
| SCHEMBL20217750 | 0.79 | CYP3A4 (0.67) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217315 | 0.78 | CYP3A4 (0.52) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217632 | 0.77 | CYP3A4 (0.52) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217458 | 0.77 | CYP3A4 (0.50) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217145 | 0.76 | CYP3A4 (0.47) | CYP3A4TTKAURKBINCENPSLC6A9 | |
| SCHEMBL20217956 | 0.76 | CYP3A4 (0.48) | CYP3A4TTKAURKBINCENPSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |