Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20218988 | 0.85 | PSMB5 (0.44) | MEN1KMT2ALTB4R2ALDH1A1USP2 | |
| SCHEMBL18464228 | 0.83 | LTB4R2 (0.50) | MEN1KMT2ALTB4R2TP53ALDH1A1 | |
| SCHEMBL18464300 | 0.83 | LTB4R2 (0.50) | MEN1KMT2ALTB4R2TP53PTGDR2 | |
| SCHEMBL18464229 | 0.78 | LTB4R2 (0.46) | MEN1KMT2ALTB4R2TP53ALDH1A1 | |
| SCHEMBL14229341 | 0.78 | LTB4R2 (0.58) | LTB4R2TP53ALDH1A1RAB9APAX8 | |
| SCHEMBL22072463 | 0.78 | RAB9A (0.42) | MEN1KMT2ATP53ALDH1A1HPGD | |
| SCHEMBL18464006 | 0.76 | HDAC1 (0.59) | LTB4R2 | |
| SCHEMBL18464077 | 0.74 | PTGDR2 (0.47) | LTB4R2ALDH1A1USP2HPGDALOX15 | |
| SCHEMBL18464078 | 0.74 | PTGDR2 (0.47) | MEN1KMT2ALTB4R2ALDH1A1USP2 | |
| SCHEMBL2157748 | 0.73 | LTB4R2 (0.48) | MEN1KMT2ALTB4R2TP53PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330259-A1 | 1,3,4-OXADIAZOLE AMIDE DERIVATIVE COMPOUND AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2018-06-06 | — | — | EP | disclosed |