Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219767 | 0.92 | TLR7 (0.44) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL15470097 | 0.88 | TLR7 (0.47) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL15470061 | 0.84 | TLR7 (0.48) | TLR7TLR8CYP1A2 | |
| SCHEMBL13195757 | 0.84 | TLR7 (0.46) | TLR7TLR8CYP1A2 | |
| SCHEMBL15470063 | 0.84 | TLR7 (0.61) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL20219729 | 0.84 | L3MBTL1 (0.44) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL15470092 | 0.83 | TLR7 (0.46) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL23472451 | 0.82 | TLR7 (0.51) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL15470064 | 0.82 | TLR7 (0.53) | TLR7TLR8CYP1A2L3MBTL1 | |
| SCHEMBL13195040 | 0.81 | APP (0.50) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |