Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20386604 | 0.84 | TLR8 (0.53) | TLR8KCNH2TLR7 | |
| SCHEMBL20219712 | 0.84 | TLR8 (0.46) | TLR8KCNH2TLR7 | |
| SCHEMBL20219576 | 0.81 | TLR8 (0.43) | TLR8KCNH2TLR7 | |
| SCHEMBL21919465 | 0.81 | TLR8 (0.43) | TLR8KCNH2TLR7 | |
| SCHEMBL21769267 | 0.77 | KCNH2 (0.49) | TLR8KCNH2TLR7 | |
| SCHEMBL20386729 | 0.77 | KCNH2 (0.49) | TLR8KCNH2TLR7 | |
| SCHEMBL23472389 | 0.72 | KCNH2 (0.47) | TLR8KCNH2TLR7 | |
| SCHEMBL20413295 | 0.71 | TLR8 (0.44) | TLR8KCNH2TLR7 | |
| SCHEMBL23472416 | 0.71 | TLR8 (0.44) | TLR8KCNH2TLR7 | |
| SCHEMBL20219744 | 0.71 | TLR7 (0.41) | TLR8KCNH2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |