Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219607 | 0.94 | TLR7 (0.52) | TLR8TLR7L3MBTL1 | |
| SCHEMBL20219645 | 0.91 | TLR8 (0.51) | TLR8TLR7L3MBTL1 | |
| SCHEMBL23472442 | 0.91 | TLR8 (0.52) | TLR8TLR7L3MBTL1 | |
| SCHEMBL20219378 | 0.90 | TLR7 (0.52) | TLR8TLR7L3MBTL1 | |
| SCHEMBL17035546 | 0.90 | TLR8 (0.62) | TLR8TLR7L3MBTL1 | |
| SCHEMBL6414963 | 0.86 | TLR7 (0.58) | TLR8TLR7L3MBTL1 | |
| SCHEMBL23472595 | 0.85 | TLR8 (0.54) | TLR8TLR7L3MBTL1 | |
| SCHEMBL23472257 | 0.85 | L3MBTL1 (0.58) | TLR8TLR7L3MBTL1 | |
| SCHEMBL23472309 | 0.84 | L3MBTL1 (0.46) | TLR8TLR7L3MBTL1 | |
| SCHEMBL20219256 | 0.84 | L3MBTL1 (0.41) | TLR8TLR7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |