Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379617 | 0.79 | FFAR4 (0.41) | OPRM1HSD11B1SLC6A2SLC6A4OPRL1 | |
| SCHEMBL2379024 | 0.69 | OPRM1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL17443879 | 0.69 | OPRM1 (0.50) | OPRM1OPRL1 | |
| SCHEMBL17443881 | 0.69 | OPRM1 (0.50) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL302953 | 0.68 | OPRM1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL17443821 | 0.67 | OPRM1 (0.44) | OPRM1HSD11B1OPRL1 | |
| SCHEMBL17443820 | 0.67 | OPRM1 (0.44) | OPRM1HSD11B1OPRL1 | |
| SCHEMBL20866632 | 0.67 | OPRM1 (0.49) | OPRM1OPRL1 | |
| Trifluoroacetic Acid SCHEMBL17444059 | 0.65 | OPRM1 (0.48) | OPRM1HSD11B1OPRL1 | |
| Trifluoroacetic Acid SCHEMBL20210987 | 0.65 | OPRM1 (0.48) | OPRM1HSD11B1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169666-B1 | SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2018-06-06 | — | — | EP | disclosed |