Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 2/20 | 0.35 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024849 | 1.00 | HTR6 (0.45) | HTR6HRH1ARPARGSCARB1 | |
| SCHEMBL12579072 | 1.00 | HTR6 (0.45) | HTR6HRH1ARPARGSCARB1 | |
| SCHEMBL2021412 | 0.87 | HTR6 (0.47) | HTR6HRH1ARPARGSCARB1 | |
| SCHEMBL12579067 | 0.87 | HTR6 (0.47) | HTR6HRH1ARPARGSCARB1 | |
| SCHEMBL2027983 | 0.87 | HTR6 (0.47) | HTR6HRH1ARPARGSCARB1 | |
| SCHEMBL14218083 | 0.87 | PARG (0.36) | HTR6HRH1PARGKCNH2MCHR1 | |
| SCHEMBL2024950 | 0.86 | HRH1 (0.34) | HTR6HRH1PARGSCARB1THRB | |
| SCHEMBL2023272 | 0.86 | HRH1 (0.34) | HTR6HRH1PARGSCARB1THRB | |
| SCHEMBL2027379 | 0.86 | HRH1 (0.34) | HTR6HRH1PARGSCARB1THRB | |
| SCHEMBL12579060 | 0.86 | HRH1 (0.34) | HTR6HRH1PARGSCARB1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968587-B2 | Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators | ELI LILLY AND COMPANY (US) | 2011-06-28 | — | — | US | disclosed |