SCHEMBL20224315

SCHEMBL20224315

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)C4(c6ccccc6-c6ccccc6-5)c5ccccc5-c5c4ccc4c5sc5ccccc54)n3)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
PDK2 Q15119 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20224317 0.97 ALOX5 (0.35) ALOX5PDK2
SCHEMBL20224314 0.96 ALOX5 (0.36) ALOX5PDK2
SCHEMBL14681623 0.95 ALOX5 (0.36) ALOX5PDK2
SCHEMBL16250111 0.95 ALOX5 (0.36) ALOX5PDK2
SCHEMBL18731666 0.94 ALOX5 (0.36) ALOX5PDK2
SCHEMBL16250095 0.93 ALOX5 (0.36) ALOX5PDK2
SCHEMBL18731675 0.93 ALOX5 (0.33) ALOX5
SCHEMBL20371114 0.92 ALOX5 (0.37) ALOX5
SCHEMBL18731677 0.92 ALOX5 (0.37) ALOX5
SCHEMBL24039490 0.92 ALOX5 (0.36) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed