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SCHEMBL20224490

SCHEMBL20224490

c1ccc(-c2ncc(-c3cc(-c4ccc5c(c4)C4(c6ccccc6-c6ccccc6-5)c5ccccc5-c5c4ccc4oc6ccccc6c54)nc(-c4ccccc4)n3)cn2)cc1

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.30
▸ KMT2A Q03164 2/20 0.30
▸ NTSR1 P30989 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20224495 0.98 KMT2A (0.32) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL20224483 0.98 KMT2A (0.32) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL20224485 0.93 KMT2A (0.35) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL20224499 0.91 KMT2A (0.34) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL18732056 0.91 KMT2A (0.34) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL20224478 0.90 WEE1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL19862244 0.89 — —
SCHEMBL20224482 0.89 PDK2 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL18156761 0.89 WEE1 (0.33) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL20224486 0.89 PDK2 (0.37) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 — — US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 — — US disclosed