Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.38 |
| ▸ | NPY4R | P50391 | 5/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19387304 | 0.94 | SIRT2 (0.37) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL14887476 | 0.93 | SIRT2 (0.39) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL19387308 | 0.93 | SIRT2 (0.39) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL14887234 | 0.93 | SIRT2 (0.39) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL16143152 | 0.93 | SIRT2 (0.38) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL21604314 | 0.93 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL18601941 | 0.92 | SIRT2 (0.38) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL16455203 | 0.91 | SIRT2 (0.39) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL19687946 | 0.91 | SIRT2 (0.39) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL15606241 | 0.91 | SIRT2 (0.38) | SIRT2SIRT1SIRT3SIRT5NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135307-B2 | Peptide-containing linkers for antibody-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2021-10-05 | — | — | US | disclosed |
| US-10772971-B2 | Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates | Mersana Therpeutics, Inc. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20180154018-A1 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135307-B2 | Peptide-containing linkers for antibody-drug conjugates | CD2BP2, DNPEP, LNPEP | SIRT2 3975/4885SIRT1 4075/4885SIRT3 4064/4885 |
| US-10772971-B2 | Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates | PBRM1, BRAP, STAMBP | SIRT2 3114/4885SIRT1 2931/4885SIRT3 2443/4885 |
| US-20180154018-A1 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | CD2BP2, DNPEP, LNPEP | SIRT2 3975/4885SIRT1 4075/4885SIRT3 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.