⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797017 | 0.71 | — | — | |
| SCHEMBL9882835 | 0.70 | KCNA4 (0.34) | — | |
| SCHEMBL17830303 | 0.69 | — | — | |
| SCHEMBL8824317 | 0.67 | — | — | |
| SCHEMBL2031403 | 0.67 | EPHX1 (0.32) | — | |
| SCHEMBL2710428 | 0.67 | — | — | |
| SCHEMBL50056 | 0.67 | — | — | |
| SCHEMBL24045297 | 0.67 | — | — | |
| SCHEMBL6127876 | 0.67 | — | — | |
| SCHEMBL17806748 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827656-B2 | Immunoproteasome inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-06-07 | — | — | US | disclosed |