Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.42 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21298878 | 0.80 | P2RX3 (0.47) | P2RX1P2RX3P2RX4POLBP2RY1 | |
| SCHEMBL20325328 | 0.80 | P2RX3 (0.47) | P2RX1P2RX3P2RX4POLBP2RY1 | |
| SCHEMBL24559535 | 0.74 | P2RX1 (0.49) | P2RX1P2RX3P2RX4P2RY1P2RY2 | |
| SCHEMBL24276629 | 0.74 | P2RX1 (0.49) | P2RX1P2RX3P2RX4P2RY1P2RY2 | |
| SCHEMBL24559534 | 0.72 | P2RX3 (0.46) | P2RX1P2RX3P2RX4P2RY1P2RY2 | |
| SCHEMBL21637015 | 0.72 | P2RY1 (0.53) | P2RX1P2RX3P2RX4POLBP2RY1 | |
| SCHEMBL24276968 | 0.72 | P2RY1 (0.48) | P2RX1P2RX3P2RX4P2RY1P2RY2 | |
| SCHEMBL21298920 | 0.72 | P2RX3 (0.49) | P2RX1P2RX3P2RX4P2RY1P2RY2 | |
| SCHEMBL22352200 | 0.72 | POLB (0.53) | P2RX1P2RX3P2RX4POLBP2RY1 | |
| SCHEMBL21636992 | 0.72 | POLB (0.53) | P2RX1P2RX3P2RX4POLBP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018100558-A2 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-06-07 | — | — | WO | disclosed |