Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224907 | 1.00 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20224836 | 0.92 | ALDH1A1 (0.46) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20224834 | 0.92 | ALDH1A1 (0.46) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20224901 | 0.91 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20225476 | 0.90 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20225030 | 0.90 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20224842 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1P2RX3 | |
| SCHEMBL20225067 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAALBMAPK1STING1 | |
| SCHEMBL22990447 | 0.83 | TYMS (0.46) | — | |
| SCHEMBL20225045 | 0.83 | TYMS (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-B1 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020229982-A1 | ANTIBODY DRUG CONJUGATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-11-19 | — | — | WO | disclosed |
| WO-2018100558-A2 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-06-07 | — | — | WO | disclosed |