SCHEMBL20224964

SCHEMBL20224964

CCCCCCCCN(CC)CC(O)COCCCC(=O)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 2/20 0.45
SIRT1 Q96EB6 1/20 0.44
SIRT3 Q9NTG7 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
KCNH2 Q12809 4/20 0.43
CCKBR P32239 1/20 0.42
ABCB1 P08183 2/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
TLR2 O60603 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19996561 0.96 ALDH1A1 (0.45) SIRT2SIRT1SIRT3ALDH1A1MEN1
SCHEMBL24180417 0.92 ABCB1 (0.48) ALDH1A1MEN1HPGDKMT2AABCB1
SCHEMBL19996565 0.92 ABCB1 (0.48) ALDH1A1MEN1HPGDKMT2AABCB1
SCHEMBL20224986 0.89 ABCB1 (0.43) ALDH1A1MEN1HPGDKMT2AABCB1
SCHEMBL25018154 0.86 ABCB1 (0.39) ALDH1A1MEN1HPGDKMT2ACCKBR
SCHEMBL20851486 0.84 ABCB1 (0.41) ALDH1A1MEN1HPGDKMT2AABCB1
SCHEMBL19996564 0.84 ALDH1A1 (0.41) ALDH1A1MEN1HPGDKMT2AABCB1
SCHEMBL25955301 0.82 ALDH1A1 (0.49) SIRT2ALDH1A1MEN1HPGDKMT2A
SCHEMBL25120950 0.81 SIRT2 (0.41) SIRT2SIRT1SIRT3MEN1KMT2A
SCHEMBL24180455 0.80 ALDH1A1 (0.40) ALDH1A1MEN1HPGDKMT2ACCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180154332-A1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING ION PAIRED-BONDED PHASES FOR SUPERCRITICAL FLUID CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION 2018-06-07 US disclosed