Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225816 | 0.94 | KDM4E (0.62) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL20225817 | 0.94 | KDM4E (0.62) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL20231598 | 0.88 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL9121600 | 0.83 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL20231599 | 0.82 | KDM4E (0.66) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL20231594 | 0.82 | KDM4E (0.66) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL20225809 | 0.82 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL14159004 | 0.82 | KDM4E (0.58) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL14158999 | 0.80 | KDM4E (0.60) | KDM4ESMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL13349920 | 0.80 | PLA2G4B (0.56) | LMNATSHRKMT2AACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155350-A1 | CELL IMPERMEABLE COELENTERAZINE ANALOGUES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155350-A1 | CELL IMPERMEABLE COELENTERAZINE ANALOGUES | SI, GLB1, MRPL21 | KDM4E 3481/4885SMN1; SMN2 3924/4885ALDH1A1 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.