SCHEMBL20230639

SCHEMBL20230639

CC1(C)c2ccccc2C(c2ccc3c(c2)Oc2cc(-c4cccc(-c5cccnc5)n4)ccc2O3)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 8/20 0.40
CYP2A6 P11509 2/20 0.38
CYP19A1 P11511 2/20 0.36
PGR P06401 1/20 0.35
CTSD P07339 2/20 0.35
PIM1 P11309 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
CYP17A1 P05093 1/20 0.34
PDK2 Q15119 1/20 0.34
KARS1 Q15046 1/20 0.33
KCNH2 Q12809 2/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20230589 0.94 CYP2A6 (0.38) BACE1CYP2A6CYP19A1PGRCTSD
SCHEMBL20230647 0.89 BACE1 (0.38) BACE1CYP2A6CYP19A1PGRCTSD
SCHEMBL20230702 0.85 CYP19A1 (0.45) BACE1CYP19A1PGRCTSDPIM1
SCHEMBL20230630 0.83 CYP2A6 (0.39) BACE1CYP2A6CYP19A1PGRNPC1
SCHEMBL20230706 0.81 CYP19A1 (0.41) BACE1CYP19A1PGRCTSDPIM1
SCHEMBL20230621 0.80 MEN1 (0.41) NPC1RAB9ALMNAPOLBMAPT
SCHEMBL22871812 0.79 BACE1 (0.39) BACE1CYP2A6CYP19A1CTSDNPC1
SCHEMBL20230619 0.79 MEN1 (0.39) LMNAMAPT
SCHEMBL20230722 0.75 NPC1 (0.44) BACE1CYP2A6CYP19A1NPC1RAB9A
SCHEMBL20230700 0.75 KMT2A (0.38) BACE1CYP19A1CTSDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10892423-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-12 US disclosed
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CCNT1 BACE1 724/4885CYP2A6 3284/4885CYP19A1 305/4885
US-10892423-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNE2, CCNT1 BACE1 724/4885CYP2A6 3284/4885CYP19A1 305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.