SCHEMBL20230739

SCHEMBL20230739

CC1(C)c2cc(-c3cc(-c4cccnc4)nc(-c4cccnc4)c3)ccc2Oc2ccc(N3c4ccccc4C(C)(C)c4ccccc43)cc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.44
BACE1 P56817 6/20 0.44
CTSD P07339 1/20 0.36
CYP11B1 P15538 5/20 0.36
CYP11B2 P19099 5/20 0.36
PDK2 Q15119 1/20 0.36
EGLN1 Q9GZT9 1/20 0.35
CYP2A6 P11509 1/20 0.35
KCNH2 Q12809 1/20 0.34
CYP17A1 P05093 1/20 0.34
LMNA P02545 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21510469 0.90 CYP19A1 (0.48) CYP19A1BACE1CYP11B1CYP11B2PDK2
SCHEMBL21510275 0.89 CYP19A1 (0.45) CYP19A1BACE1CTSDCYP11B1CYP11B2
SCHEMBL22871842 0.89 CYP19A1 (0.40) CYP19A1BACE1CTSDCYP11B1CYP11B2
SCHEMBL22871815 0.88 CYP19A1 (0.49) CYP19A1BACE1CYP11B1CYP11B2PDK2
SCHEMBL22871816 0.86 KDM4E (0.37) CYP19A1BACE1CTSDLMNAALDH1A1
SCHEMBL22871812 0.85 BACE1 (0.39) CYP19A1BACE1CTSDCYP11B1CYP11B2
SCHEMBL21973898 0.84 CYP19A1 (0.54) CYP19A1CYP11B1CYP11B2PDK2EGLN1
SCHEMBL20230748 0.83 CYP2A6 (0.38) CYP19A1BACE1CTSDCYP11B1CYP11B2
SCHEMBL20230616 0.82 ADORA1 (0.34) BACE1CTSDALDH1A1MAPT
SCHEMBL21510464 0.82 PDK2 (0.40) CYP19A1BACE1CYP11B1CYP11B2PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10892423-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-12 US disclosed
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180159050-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CCNT1 CYP19A1 305/4885BACE1 724/4885CTSD 2849/4885
US-10892423-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNE2, CCNT1 CYP19A1 305/4885BACE1 724/4885CTSD 2849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.