Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 4/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12579057 | 1.00 | SCARB1 (0.36) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL12579062 | 0.94 | HRH1 (0.36) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL2023590 | 0.90 | HTR6 (0.36) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL12579051 | 0.90 | HTR6 (0.36) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL2026761 | 0.89 | SCARB1 (0.36) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL12579070 | 0.89 | SCARB1 (0.36) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL2021312 | 0.88 | SCARB1 (0.40) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL12579055 | 0.88 | SCARB1 (0.40) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL2027138 | 0.88 | SCARB1 (0.40) | SCARB1HRH1HTR6PARGFNTA | |
| SCHEMBL2025539 | 0.88 | SCARB1 (0.40) | SCARB1HRH1HTR6PARGFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968587-B2 | Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators | ELI LILLY AND COMPANY (US) | 2011-06-28 | — | — | US | disclosed |