Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822605 | 0.99 | KDM4E (0.50) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL16171208 | 0.96 | KDM4E (0.47) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL12811614 | 0.94 | KDM4E (0.51) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL15946326 | 0.94 | L3MBTL1 (0.55) | KDM4EATML3MBTL1AHRALDH1A1 | |
| SCHEMBL18381861 | 0.94 | KDM4E (0.55) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL17245948 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL26329809 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL9890473 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL16171188 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1AHRMAOA | |
| SCHEMBL15946288 | 0.93 | KDM4E (0.50) | KDM4EATML3MBTL1AHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548481-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018100029-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | NQO1, DDT, ETV6 | KDM4E 1555/4885ATM 4662/4885L3MBTL1 3899/4885 |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | NQO1, DDT, ETV6 | KDM4E 1555/4885ATM 4662/4885L3MBTL1 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.