Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14849836 | 0.99 | KDM4E (0.42) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL16282967 | 0.99 | KDM4E (0.42) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL14822420 | 0.99 | KDM4E (0.42) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL14822630 | 0.98 | L3MBTL1 (0.41) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL10001507 | 0.98 | L3MBTL1 (0.41) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL16283013 | 0.98 | L3MBTL1 (0.41) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL10001424 | 0.98 | L3MBTL1 (0.41) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL18254308 | 0.98 | L3MBTL1 (0.41) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL15337978 | 0.98 | KDM4E (0.43) | KDM4EATML3MBTL1HDAC4TSPO | |
| SCHEMBL18062365 | 0.97 | KDM4E (0.38) | KDM4EATML3MBTL1HDAC4TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548481-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018100029-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | NQO1, DDT, ETV6 | KDM4E 1555/4885ATM 4662/4885L3MBTL1 3899/4885 |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | NQO1, DDT, ETV6 | KDM4E 1555/4885ATM 4662/4885L3MBTL1 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.