Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MMP15 | P51511 | 1/20 | 0.39 |
| ▸ | MMP16 | P51512 | 1/20 | 0.39 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820655 | 1.00 | ESR1 (0.51) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL27661436 | 1.00 | ESR1 (0.51) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL820930 | 1.00 | ESR1 (0.51) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL28750802 | 1.00 | ESR1 (0.51) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL13048137 | 0.89 | MTNR1A (0.44) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL3410085 | 0.89 | MTNR1A (0.44) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL13048165 | 0.89 | MTNR1A (0.44) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL3410091 | 0.89 | MTNR1A (0.44) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL3412451 | 0.89 | MTNR1A (0.44) | ESR1ESR2CA1CA2ACHE | |
| SCHEMBL3412455 | 0.89 | MTNR1A (0.44) | ESR1ESR2CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018102399-A1 | METHODS OF DOSE ADMINISTRATION FOR TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES | T3D THERAPEUTICS, INC. (US) | 2018-06-07 | — | — | WO | disclosed |