Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | FAAH | O00519 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ME2 | P23368 | 1/20 | 0.64 |
| ▸ | ME1 | P48163 | 1/20 | 0.64 |
| ▸ | ME3 | Q16798 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897923 | 0.94 | KDM4E (0.77) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL10729724 | 0.94 | KDM4E (0.77) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL4526073 | 0.87 | KDM4E (0.68) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL570715 | 0.86 | CYP2C9 (0.71) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL4776281 | 0.86 | CYP2C9 (0.71) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL14590550 | 0.85 | KDM4E (0.71) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL4300084 | 0.85 | KDM4E (0.93) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| Hydrochloric Acid SCHEMBL7128759 | 0.85 | POLB (0.72) | KDM4ECYP2C9CYP2C19POLBFAAH | |
| SCHEMBL4051171 | 0.85 | RAB9A (0.69) | KDM4ECYP2C9CYP2C19POLBGLA | |
| SCHEMBL420582 | 0.85 | RAB9A (0.69) | KDM4ECYP2C9CYP2C19POLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331864-B1 | 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2021-11-03 | — | — | EP | disclosed |
| US-10717716-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2020-07-21 | — | — | US | disclosed |
| EP-3331864-A2 | 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2018-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717716-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | HDAC1, HDAC5, HDAC2 | KDM4E 1285/4885CYP2C9 2023/4885CYP2C19 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.