SCHEMBL2023682

SCHEMBL2023682

Cc1cc(CCO)ccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.46
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ALOX5 P09917 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
BACE1 P56817 1/20 0.42
KCNQ2 O43526 1/20 0.41
FFAR1 O14842 1/20 0.40
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
NR3C2 P08235 2/20 0.37
GRM5 P41594 1/20 0.37
CYP4F2 P78329 3/20 0.37
CYP4A11 Q02928 3/20 0.37
CA2 P00918 1/20 0.37
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
DYRK1A Q13627 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30324476 1.00 UHRF1 (0.46) UHRF1KDM4EALDH1A1ALOX5GAA
SCHEMBL4282403 0.88 UHRF1 (0.43) UHRF1KCNQ2FFAR1RECQLNR3C2
SCHEMBL4355540 0.87 UHRF1 (0.54) UHRF1KCNQ2FFAR1NR3C2GRM5
SCHEMBL24258739 0.85 BCHE (0.41) UHRF1KCNQ2FFAR1CYP4F2CYP4A11
SCHEMBL4358691 0.83 UHRF1 (0.50) UHRF1KCNQ2FFAR1NR3C2GRM5
SCHEMBL29674439 0.83
SCHEMBL203588 0.83
SCHEMBL24010814 0.82 PDCD1 (0.43) UHRF1KDM4EALDH1A1GAAKCNQ2
SCHEMBL487318 0.81 UHRF1 (0.48) UHRF1KDM4EKCNQ2FFAR1NR3C2
SCHEMBL3915085 0.79 LOXL2 (0.50) UHRF1KDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112279984-A Method for preparing catalytic nano-microspheres by polymerization-induced self-assembly 浙江理工大学 2021-01-29 CN claimed
CN-112279984-B Method for preparing catalytic nano microsphere by polymerization-induced self-assembly 浙江理工大学 2023-05-09 CN disclosed
CN-112279984-B Method for preparing catalytic nano microsphere by polymerization-induced self-assembly 浙江理工大学 2023-05-09 CN disclosed
CN-112279984-A Method for preparing catalytic nano-microspheres by polymerization-induced self-assembly 浙江理工大学 2021-01-29 CN disclosed
CN-112279984-A Method for preparing catalytic nano-microspheres by polymerization-induced self-assembly 浙江理工大学 2021-01-29 CN disclosed
WO-2019148005-A1 INHIBITORS OF CBL-B AND METHODS OF USE THEREOF NURIX THERAPEUTICS, INC. (US) 2019-08-01 WO disclosed
WO-2016130396-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. (US) 2016-08-18 WO disclosed
US-7956060-B2 Pyrimidine derivative compound KYOWA HAKKO KIRIN CO., LTD. (JP) 2011-06-07 US disclosed
US-7635775-B2 Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists ELAN PHARMACEUTICALS, INC. (US) 2009-12-22 US disclosed
US-7635775-B2 Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists ELAN PHARMACEUTICALS, INC. (US) 2009-12-22 US disclosed
WO-2003016428-A2 TRIBOLUMINESCENT MATERIALS AND DEVICES CONTAINING THEM QINETIQ LIMITED (GB) 2003-02-27 WO disclosed
EP-1165076-A4 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO INC (US) 2002-05-15 EP disclosed
EP-1165076-A1 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE Merck & Co., Inc. (US) 2002-01-02 EP disclosed
US-6291596-B1 CONTACTING OLEFINICALLY UNSATURATED COMPOUND WITH HYDROGEN IN THE PRESENCE OF A HYDROGENATION CATALYST COMPRISING TITANIUM OR ZIRCONIUM OR HAFNIUM COMPOUND IN AN INERT, ORGANIC SOLVENT JSR CORPORATION (JP) 2001-09-18 US disclosed
WO-2000053181-A1 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO., INC. (US) 2000-09-14 WO disclosed
EP-0974602-A1 Catalyst and process for hydrogenating olefinically unsaturated compound JSR Corporation (JP) 2000-01-26 EP disclosed
US-4242516-A Fluorinated amphoteric surfactants CIBA-GEIGY CORPORATION (US) 1980-12-30 US disclosed
US-4161602-A Fluorinated amphoteric and cationic surfactants containing a pyridinium moiety CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4161590-A Fluorinated amphoteric and cationic surfactants CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4069244-A THIO-CARBOXYLIC ACIDS CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed