Serine

Serine

SCHEMBL2023740

N[C@@H](CO)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 4/20 0.59
PTGS1 P23219 1/20 0.55
SLC7A11 Q9UPY5 1/20 0.55
SLC1A3 P43003 3/20 0.50
SLC1A2 P43004 3/20 0.50
GSR P00390 2/20 0.50
GRIK1 P39086 2/20 0.50
GRIK2 Q13002 2/20 0.50
GRM1 Q13255 2/20 0.50
GRM2 Q14416 2/20 0.50
SLC7A5 Q01650 1/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
CYP1A2 P05177 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL6929758 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL4455818 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL2023739 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL6929773 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL6520912 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
(D)-Serine SCHEMBL6038168 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
(D)-Serine SCHEMBL43094 1.00
Serine SCHEMBL1332181 1.00
(D)-Serine SCHEMBL6660617 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL6520918 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101781325-A Gallium salicylaldehyde amino acid Schiff base quaternary coordination compound, preparation method and application thereof UNIV BEIJING NORMAL 2010-07-21 CN claimed
EP-1771440-A4 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES AMGEN INC (US) 2009-09-02 EP claimed
EP-1771440-A1 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES Amgen, Inc (US) 2007-04-11 EP claimed
WO-2006014645-A1 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES AMGEN INC. (US) 2006-02-09 WO claimed
US-5849695-A Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-12-15 US claimed
CN-114008452-A Method for evaluating food related to cognitive function 味之素株式会社 2022-02-01 CN disclosed
CN-108424944-B Optimized production method and culture medium of candicidin 华东理工大学 2021-07-27 CN disclosed
CN-113025573-A Liquid supplementing culture medium and method for culturing and inducing hematopoietic stem cells to differentiate into megakaryocyte 中国人民解放军军事科学院军事医学研究院 2021-06-25 CN disclosed
EP-3679065-A1 SIGNALING AND ANTIGEN-PRESENTING BIFUNCTIONAL RECEPTORS (SABR) California Institute of Technology (US) 2020-07-15 EP disclosed
EP-3622081-A1 PROCESS FOR PRODUCING AN AZAPHILONE IN TALAROMYCES ATROROSEUS Danmarks Tekniske Universitet (DK) 2020-03-18 EP disclosed
CN-110150760-A A kind of aerosol generation system 钟术光 2019-08-23 CN disclosed
CN-110168370-A METHODS FOR IDENTIFYING CANDIDATE BIOMARKERS 健康之语公司 2019-08-23 CN disclosed
CN-1151761-A Subtilisin BPN' variants with reduced adsorption and increased hydrolysis PROCTER & GAMBLE (US) 1997-06-11 CN disclosed
EP-0652897-A4 PEPTIDE INHIBITORS OF SELECTIN BINDING. CENTOCOR INC (US) 1995-09-20 EP disclosed
EP-0652897-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR INC. (US) 1995-05-17 EP disclosed
EP-0584244-A1 PEPTIDE INHIBITORS OF INFLAMMATION THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 1994-03-02 EP disclosed
WO-1993024527-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR, INC. (US) 1993-12-09 WO disclosed
WO-1992020708-A1 PEPTIDE INHIBITORS OF INFLAMMATION BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) 1992-11-26 WO disclosed
US-4503035-A HUMAN LEUKOCYTE INTERFERON HOFFMANN-LA ROCHE INC. (US) 1985-03-05 US disclosed
US-4463090-A PROENZYMES COUPLED TO LIGANDS; ACTIVATION; SENSITIVITY RAPIDEX LIMITED 1984-07-31 US disclosed