Serine

Serine

SCHEMBL4455818

NC(CO)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 4/20 0.59
PTGS1 P23219 1/20 0.55
SLC7A11 Q9UPY5 1/20 0.55
SLC1A3 P43003 3/20 0.50
SLC1A2 P43004 3/20 0.50
GSR P00390 2/20 0.50
GRIK1 P39086 2/20 0.50
GRIK2 Q13002 2/20 0.50
GRM1 Q13255 2/20 0.50
GRM2 Q14416 2/20 0.50
SLC7A5 Q01650 1/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
CYP1A2 P05177 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL6929758 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL2023739 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL6929773 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL6520912 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
(D)-Serine SCHEMBL6038168 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL2023740 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
(D)-Serine SCHEMBL43094 1.00
Serine SCHEMBL1332181 1.00
(D)-Serine SCHEMBL6660617 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2
Serine SCHEMBL6520918 1.00 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849695-A Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-12-15 US claimed
CN-113025573-A Liquid supplementing culture medium and method for culturing and inducing hematopoietic stem cells to differentiate into megakaryocyte 中国人民解放军军事科学院军事医学研究院 2021-06-25 CN disclosed
WO-2020231059-A1 ACTIVATED LYMPHOCYTE AND PREPARATION METHOD THEREFOR (주)녹십자셀 2020-11-19 WO disclosed
EP-3313994-A1 CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2018-05-02 EP disclosed
WO-2016207219-A1 CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-12-29 WO disclosed
US-20090192554-A1 BIOABSORBABLE BLOCK COPOLYMER CONFLUENT SURGICAL, INC. 2009-07-30 US disclosed
US-4463090-A PROENZYMES COUPLED TO LIGANDS; ACTIVATION; SENSITIVITY RAPIDEX LIMITED 1984-07-31 US disclosed