SCHEMBL20237404

SCHEMBL20237404

CCOS(=O)(=O)C(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.33
CA1 P00915 5/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27662404 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL27641892 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL20237401 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL27641979 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL27641894 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL27662373 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL27641896 1.00 CA2 (0.33) CA2CA1F2PRSS1PRSS2
SCHEMBL27662401 0.92 CA1 (0.36) CA2CA1
SCHEMBL27641891 0.85 CA1 (0.40) CA2CA1
SCHEMBL29126717 0.82 CA2 (0.47) CA2CA1F2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1686425-B1 METHOD FOR FORMING MULTILAYER RESIST DAIKIN IND LTD (JP) 2018-06-13 EP disclosed