Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973213 | 0.96 | MAPK1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL12655445 | 0.80 | ALDH1A1 (0.56) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL230874 | 0.79 | TDP1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL30198949 | 0.79 | TDP1 (0.60) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL397773 | 0.79 | MAPK1 (0.77) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| Ethane SCHEMBL27611887 | 0.78 | HSD17B10 (0.68) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| Water SCHEMBL27730559 | 0.78 | TDP1 (0.58) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| Hydrochloric Acid SCHEMBL28855008 | 0.78 | TDP1 (0.58) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| Ethane SCHEMBL27839335 | 0.75 | HSD17B10 (0.65) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| Ethane SCHEMBL27905373 | 0.75 | HSD17B10 (0.65) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |