Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239689 | 0.98 | TSHR (0.37) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 | |
| SCHEMBL20239867 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239711 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239839 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239701 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239702 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239743 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239827 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239789 | 0.92 | THRB (0.41) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL20239870 | 0.90 | THRB (0.44) | TSHRALDH1A1MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |