Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PPM1D | O15297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20243736 | 1.00 | CTDSP1 (0.32) | CTDSP1TDP1HPGDKDM4EALDH1A1 | |
| SCHEMBL6817518 | 0.87 | — | — | |
| SCHEMBL6817519 | 0.87 | — | — | |
| SCHEMBL6817521 | 0.87 | — | — | |
| SCHEMBL6818084 | 0.80 | STAT3 (0.34) | — | |
| SCHEMBL6817522 | 0.80 | STAT3 (0.34) | — | |
| SCHEMBL7152354 | 0.80 | STAT3 (0.34) | — | |
| SCHEMBL7147727 | 0.80 | STAT3 (0.34) | — | |
| SCHEMBL13531907 | 0.79 | ESR2 (0.38) | CTDSP1TDP1HPGDKDM4EALDH1A1 | |
| SCHEMBL20243244 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162884-A1 | POLYENE COMPOUND, PREPARATION METHOD AND USE THEREOF | CHEMVON BIOTECHNOLOGY CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| US-20180162884-A1 | POLYENE COMPOUND, PREPARATION METHOD AND USE THEREOF | CHEMVON BIOTECHNOLOGY CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| US-9994598-B1 | Polyene compound, preparation method and use thereof | CHEMVON BIOTECHNOLOGY CO., LTD. (CN) | 2018-06-12 | — | — | US | disclosed |
| US-9994598-B1 | Polyene compound, preparation method and use thereof | CHEMVON BIOTECHNOLOGY CO., LTD. (CN) | 2018-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162884-A1 | POLYENE COMPOUND, PREPARATION METHOD AND USE THEREOF | PARG, SQLE, PCBP1 | CTDSP1 1115/4885TDP1 3566/4885HPGD 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.