Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817522 | 1.00 | STAT3 (0.34) | STAT3 | |
| SCHEMBL7152354 | 1.00 | STAT3 (0.34) | STAT3 | |
| SCHEMBL6818084 | 1.00 | STAT3 (0.34) | STAT3 | |
| SCHEMBL7146669 | 0.83 | STAT3 (0.30) | STAT3 | |
| SCHEMBL8071840 | 0.83 | STAT3 (0.30) | STAT3 | |
| SCHEMBL8077670 | 0.83 | STAT3 (0.30) | STAT3 | |
| SCHEMBL6817670 | 0.83 | STAT3 (0.30) | STAT3 | |
| SCHEMBL8071841 | 0.83 | STAT3 (0.30) | STAT3 | |
| SCHEMBL20243249 | 0.83 | STAT3 (0.30) | STAT3 | |
| SCHEMBL8071839 | 0.83 | STAT3 (0.30) | STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171605-A1 | 3-Epi compounds of vitamin D3 and uses thereof | WOMEN AND INFANTS HOSPITAL (US) | 2003-09-11 | — | — | US | disclosed |
| US-20010007907-A1 | 3-EPI COMPOUNDS OF VITAMIN D3 AND USES THEREOF | WOMEN AND INFANTS HOSPITAL | 2001-07-12 | — | — | US | disclosed |
| US-6040461-A | Synthesis of 3-epi vitamin D3 metabolites and analogs | HOFFMANN-LA ROCHE INC. (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0957098-A1 | Intermediates for the synthesis of 3-epi vitamin D3 metabolites and analogs | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998051663-A2 | 3-EPI COMPOUNDS OF VITAMIN D3 AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007907-A1 | 3-EPI COMPOUNDS OF VITAMIN D3 AND USES THEREOF | VDR, CYP24A1, CYP2R1 | STAT3 2449/4885 |
| US-20030171605-A1 | 3-Epi compounds of vitamin D3 and uses thereof | VDR, CYP24A1, CYP2R1 | STAT3 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.