Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.63 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.63 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.63 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | NMT1 | P30419 | 5/20 | 0.53 |
| ▸ | NMT2 | O60551 | 4/20 | 0.53 |
| ▸ | RRM1 | P23921 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12015618 | 0.97 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL18653408 | 0.97 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL22991807 | 0.91 | GNAI3 (0.80) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL17087672 | 0.91 | GNAI3 (0.59) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL18159952 | 0.91 | GNAI3 (0.63) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL16301980 | 0.90 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL18653407 | 0.89 | GNAI3 (0.60) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL22750084 | 0.89 | GNAI3 (0.57) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL17977155 | 0.89 | GNAI3 (0.57) | GNAI3GNAO1GNAI1SIRT6SIRT1 | |
| SCHEMBL17087724 | 0.89 | GNAI3 (0.57) | GNAI3GNAO1GNAI1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994605-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | UNIVERSITAET BASEL (CH) | 2018-06-12 | — | — | US | disclosed |