Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | TERT | O14746 | 4/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 5/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20245010 | 0.87 | NMT1 (0.46) | NMT2NMT1TLR2NPBWR1GLP1R | |
| SCHEMBL20244915 | 0.84 | NMT1 (0.44) | NMT2NMT1TLR2NPBWR1GLP1R | |
| SCHEMBL20244914 | 0.83 | TLR2 (0.44) | NMT2NMT1TLR2NPBWR1GLP1R | |
| SCHEMBL17922802 | 0.82 | GNAI3 (0.48) | GNAI3GNAO1GNAI1CA2TLR2 | |
| SCHEMBL19543639 | 0.80 | GNAI3 (0.62) | GNAI3GNAO1GNAI1CA2TLR2 | |
| SCHEMBL21778353 | 0.79 | GLP1R (0.47) | NMT2NMT1TLR2GLP1R | |
| SCHEMBL12344749 | 0.79 | GNAI3 (0.57) | GNAI3GNAO1GNAI1CA2TLR2 | |
| SCHEMBL13790281 | 0.79 | GNAI3 (0.57) | GNAI3GNAO1GNAI1CA2TLR2 | |
| SCHEMBL20244935 | 0.79 | MEN1 (0.41) | NMT2NMT1TLR2NPBWR1GLP1R | |
| SCHEMBL26839212 | 0.78 | GNAI3 (0.55) | GNAI3GNAO1GNAI1CA2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041468-B1 | CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-06-13 | — | — | EP | disclosed |