Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20246141 | 0.84 | — | — | |
| SCHEMBL20245734 | 0.77 | MEN1 (0.39) | — | |
| SCHEMBL20245770 | 0.77 | POLB (0.37) | POLBL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL20245586 | 0.71 | HCRTR2 (0.35) | L3MBTL1ALDH1A1 | |
| SCHEMBL21961899 | 0.70 | POLB (0.38) | POLBL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL20245833 | 0.63 | ALDH1A1 (0.35) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL3519499 | 0.61 | POLB (0.50) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL20245705 | 0.61 | — | — | |
| SCHEMBL20253619 | 0.60 | TSHR (0.32) | POLBL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL7931225 | 0.60 | MEN1 (0.32) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172212-B1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-06-13 | — | — | EP | disclosed |