SCHEMBL20246767

SCHEMBL20246767

NC1CCC(/C=C/C2CCC(c3ccccc3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
KDM1A O60341 7/20 0.41
MAOB P27338 6/20 0.41
MAOA P21397 4/20 0.41
KDM1B Q8NB78 1/20 0.41
RCOR1 Q9UKL0 1/20 0.41
GRIN2B Q13224 1/20 0.40
SPHK1 Q9NYA1 1/20 0.39
CYP2D6 P10635 4/20 0.39
CYP2C19 P33261 3/20 0.39
AKR1C3 P42330 1/20 0.38
AKR1C1 Q04828 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
TSHR P16473 1/20 0.38
CYP2B6 P20813 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22136958 0.88 SLC18A3 (0.54) SLC18A3SIGMAR1KDM1AMAOBMAOA
SCHEMBL430336 0.88 SLC18A3 (0.54) SLC18A3SIGMAR1KDM1AMAOBMAOA
SCHEMBL430023 0.88 SLC18A3 (0.54) SLC18A3SIGMAR1KDM1AMAOBMAOA
SCHEMBL51322 0.88 SLC18A3 (0.54) SLC18A3SIGMAR1KDM1AMAOBMAOA
Hydrochloric Acid SCHEMBL4040775 0.86 SLC18A3 (0.52) SLC18A3SIGMAR1KDM1AMAOBMAOA
Hydrochloric Acid SCHEMBL15319877 0.86 SLC18A3 (0.52) SLC18A3SIGMAR1KDM1AMAOBMAOA
Hydrochloric Acid SCHEMBL10849250 0.86 SLC18A3 (0.52) SLC18A3SIGMAR1KDM1AMAOBMAOA
Hydrochloric Acid SCHEMBL4534403 0.84 SLC18A3 (0.50) SLC18A3SIGMAR1KDM1AMAOBMAOA
SCHEMBL8520147 0.82 SLC18A3 (0.50) SLC18A3SIGMAR1GRIN2BCYP2D6CYP2C19
SCHEMBL7549602 0.82 SLC18A3 (0.50) SLC18A3SIGMAR1GRIN2BCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3093328-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-13 EP disclosed