SCHEMBL7549602

SCHEMBL7549602

C(=C/C1CCC(c2ccccc2)CC1)\C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 8/20 0.50
CYP2D6 P10635 3/20 0.47
CYP2C19 P33261 1/20 0.47
SIGMAR1 Q99720 2/20 0.46
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALDH1A1 P00352 1/20 0.45
APEX1 P27695 1/20 0.45
BLM P54132 1/20 0.45
GRIN2B Q13224 2/20 0.41
GRIN1 Q05586 1/20 0.41
CYP11B2 P19099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520147 1.00 SLC18A3 (0.50) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL7549605 1.00 SLC18A3 (0.50) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL10091181 0.82 ESR2 (0.50) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL13586321 0.82 SLC18A3 (0.44) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL20246767 0.82 SLC18A3 (0.44) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL18411543 0.82 SLC18A3 (0.44) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL18773575 0.81 HDAC2 (0.40) SLC18A3
SCHEMBL447032 0.80 SLC18A3 (0.63) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL790829 0.80 SLC18A3 (0.63) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR
SCHEMBL42833 0.80 SLC18A3 (0.63) SLC18A3CYP2D6CYP2C19SIGMAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1213339-A1 Liquid crystalline medium MERCK PATENT GmbH (DE) 2002-06-12 EP disclosed
US-5997766-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-12-07 US disclosed
US-5911912-A POLYMERS FOR LIQUID CRYSTAL POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1999-06-15 US disclosed
US-5723682-A LIQUID CRYSTAL MEDIA MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-03-03 US disclosed