Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.49 |
| ▸ | CA1 | P00915 | 8/20 | 0.49 |
| ▸ | CA4 | P22748 | 7/20 | 0.49 |
| ▸ | CA6 | P23280 | 6/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14954350 | 0.89 | CA2 (0.62) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL3392835 | 0.85 | CA1 (0.45) | CA2CA1CA4CA6HSP90AA1 | |
| SCHEMBL3155413 | 0.85 | CA2 (0.57) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL18480665 | 0.82 | CA1 (0.50) | CA2CA1CA4CA6HSP90AA1 | |
| SCHEMBL5534604 | 0.82 | PDE4A (0.52) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL28312125 | 0.82 | PDE4A (0.52) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL29256827 | 0.81 | PDE4A (0.41) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL147850 | 0.81 | CA2 (0.47) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL30829272 | 0.81 | CA2 (0.47) | CA2CA1CA4CA6PDE4A | |
| SCHEMBL4270114 | 0.81 | HSP90AA1 (0.49) | CA2CA1CA4CA6HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343944-B2 | Trisubstituted boron-containing molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| EP-2458995-A1 | TRISUBSTITUTED BORON-CONTAINING MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2012-06-06 | — | — | EP | disclosed |
| US-20110136763-A1 | TRISUBSTITUTED BORON-CONTAINING MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136763-A1 | TRISUBSTITUTED BORON-CONTAINING MOLECULES | BCL6B, BCL6, BLK | CA2 1357/4885CA1 4115/4885CA4 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.