Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249311 | 0.83 | HRH4 (0.33) | HRH4 | |
| SCHEMBL20249270 | 0.83 | TRPV1 (0.30) | — | |
| SCHEMBL18291181 | 0.81 | HRH4 (0.33) | HRH4HRH3 | |
| SCHEMBL20249317 | 0.81 | SOS1 (0.32) | — | |
| SCHEMBL20249235 | 0.78 | HRH4 (0.48) | HRH4HRH3 | |
| SCHEMBL20249271 | 0.77 | HRH4 (0.32) | HRH4 | |
| SCHEMBL20249284 | 0.77 | BPTF (0.33) | HRH3 | |
| SCHEMBL20249303 | 0.74 | ALDH1A1 (0.49) | — | |
| SCHEMBL20249295 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL20249336 | 0.70 | CYP11B1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180161329-A1 | PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TEIJIN PHARMA LIMITED (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161329-A1 | PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | CDK4, CDK6, CDK16 | HRH4 1763/4885HRH3 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.