SCHEMBL2024988

SCHEMBL2024988

CC(=NNC(N)=S)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
GLA P06280 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ATM Q13315 1/20 0.46
METTL3 Q86U44 1/20 0.46
HPGD P15428 1/20 0.43
CTSK P43235 1/20 0.41
TAS2R38 P59533 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2024987 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL1641313 0.84 ALDH1A1 (0.47) ALDH1A1KDM4EATMMETTL3HPGD
SCHEMBL23907305 0.81 ALDH1A1 (0.48) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL2173552 0.81 ALDH1A1 (0.48) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL2173551 0.81 ALDH1A1 (0.48) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL7859358 0.77 ALDH1A1 (0.46) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL2949847 0.77 ALDH1A1 (0.46) ALDH1A1KDM4EMEN1NPC1GLA
SCHEMBL17234569 0.77 ALDH1A1 (0.46) ALDH1A1KDM4EMEN1NPC1GLA
Hydrochloric Acid SCHEMBL7526024 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EMEN1NPC1GLA
Hydrochloric Acid SCHEMBL7526029 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EMEN1NPC1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111705312-A Chemical tin plating solution and preparation method and application thereof 信丰正天伟电子科技有限公司 2020-09-25 CN disclosed
US-9340523-B2 Certain dipeptidyl peptidase inhibitors FOCHON PHARMA, INC. (US) 2016-05-17 US disclosed
EP-2521721-B1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2014-10-01 EP disclosed
US-20140213590-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS FOCHON PHARMA, INC. (US) 2014-07-31 US disclosed
US-8648073-B2 Certain dipeptidyl peptidase inhibitors FOCHON PHARMA, INC. (US) 2014-02-11 US disclosed
US-8444774-B2 Flux composition and process for use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-05-21 US disclosed
EP-2521721-A1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS Shanghai Fochon Pharmaceutical Co. Ltd (CN) 2012-11-14 EP disclosed
WO-2011079778-A1 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2011-07-07 WO disclosed
US-20110160212-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS FOCHON PHARMA, INC. 2011-06-30 US disclosed
US-7780801-B2 for soldering flip chip surfaces; fluxing agent comprises keto acid such as levulinic acid or acetylbutyric acid; mixture of tacky solvent (ethoxylated glycerol) with non-tacky solvent (methanol) INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-08-24 US disclosed
US-20100175790-A1 New Flux Composition and Process For Use Thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-07-15 US disclosed
US-20080124568-A1 New flux composition and process for use thereof GLOBALFOUNDRIES INC. (KY) 2008-05-29 US disclosed
WO-1999031096-A1 PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS SHAMAN PHARMACEUTICALS, INC. (US) 1999-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160212-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS DPP4, DPP3, DPP8 ALDH1A1 908/4885KDM4E 3742/4885MEN1 2858/4885
US-20140213590-A1 CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS DPP4, DPP3, DPP8 ALDH1A1 908/4885KDM4E 3742/4885MEN1 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.