Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 20/20 | 0.65 |
| ▸ | VEGFA | P15692 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560819 | 0.79 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560936 | 0.79 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL19872283 | 0.79 | EPAS1 (0.64) | EPAS1VEGFA | |
| SCHEMBL19865227 | 0.77 | EPAS1 (0.52) | EPAS1VEGFA | |
| SCHEMBL24317771 | 0.75 | EPAS1 (0.85) | EPAS1VEGFA | |
| SCHEMBL20253146 | 0.74 | EPAS1 (0.53) | EPAS1VEGFA | |
| SCHEMBL16560977 | 0.73 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16556076 | 0.73 | EPAS1 (0.75) | EPAS1VEGFA | |
| SCHEMBL30856874 | 0.73 | EPAS1 (0.75) | EPAS1VEGFA | |
| SCHEMBL21362883 | 0.72 | VEGFA (0.48) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162807-A1 | AROMATIC COMPOUNDS AND USES THEREOF | PELOTON THERAPEUTICS, INC. | 2018-06-14 | — | — | US | disclosed |
| US-20180162807-A1 | AROMATIC COMPOUNDS AND USES THEREOF | PELOTON THERAPEUTICS, INC. | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162807-A1 | AROMATIC COMPOUNDS AND USES THEREOF | HIF1A, HIF1AN, VHL | EPAS1 13/4885VEGFA 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.