Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254446 | 0.88 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL20254433 | 0.84 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL26270371 | 0.81 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL29361216 | 0.81 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL20242439 | 0.81 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL26270367 | 0.80 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL20254444 | 0.77 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL24111133 | 0.76 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL30324530 | 0.76 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL20254443 | 0.75 | RIPK1 (0.56) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018107060-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2018-06-14 | — | — | WO | disclosed |