Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824997 | 0.70 | MGMT (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23174814 | 0.70 | CYP1A2 (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL25321212 | 0.67 | KCNH2 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL3250839 | 0.67 | KDM4E (0.34) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1088848 | 0.67 | MAPK1 (0.37) | MMP13MMP14KDM4EUSP2ALDH1A1 | |
| SCHEMBL15686910 | 0.67 | POLB (0.36) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18138251 | 0.67 | KDM4E (0.40) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL10680395 | 0.67 | KMT2A (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL615172 | 0.67 | SYK (0.35) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL4952656 | 0.66 | CA2 (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968587-B2 | Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators | ELI LILLY AND COMPANY (US) | 2011-06-28 | — | — | US | disclosed |